Propylene glycol is generally considered non-toxic by the US FDA and is safe for different commercial
preparations. However, it can jeopardize health if substance is mishandled. It is very important that
care should be taken in following precautions and to administer proper first aid treatment in case of an
accident.
Ingestion Problem
Consuming small amounts of propylene glycol poses no substantial risks, but intake of greater than 3-4
oz. (or approximately 100 ml.) may cause stomach pain, nausea, or even vomiting. Medical assessment
may reveal hemoglobinuric nephrosis and surface changes in EEG, especially with patients suffering
from kidney problems. Long-term ingestion can cause lactic acidosis and seizures. Give two to four
glasses of water or milk to dilute the substance if ingested. However, DO NOT induce vomiting if taken
in large amounts. Call instead the local poison control center to mitigate the problem and to get proper
guidance. Victim should be constantly monitored for signs of central nervous system dysfunction and
acidosis.
Inhalation Problem
Propylene glycol does not usually cause inhalation problems but can cause breathing difficulties if
used in areas with poor ventilation. Transfer victim immediately in areas with fresh, circulating air.
Supplement with oxygen if symptoms persist and seek medical help.
Skin Exposure
Skin exposure might cause mild irritation. Remove any tainted clothing and wash exposed skin areas
with plenty of water and soap. Irritation subsides usually. Apply an antibacterial cream if exposed areas
develop rashes.
Eye Exposure
Liquid and vaporized propylene glycol can cause mild eye irritation for some people. If it causes stinging
and redness, wash eyes with cold, running water to soothe. Victims should remove and clean contact
lenses and eyeglasses as well.
Chronic exposure
Propylene glycol may be detrimental for the reproductive system and natal development. Laboratory
studies reveal it to be a suspected teratogen. It can also depress the central nervous system if taken in
large doses.
For more detailed information, visit J.T. Baker (http://www.jtbaker.com/msds/englishhtml/p6928.htm)
or the University of Akron database (http://www.jtbaker.com/msds/englishhtml/p6928.htm).
preparations. However, it can jeopardize health if substance is mishandled. It is very important that
care should be taken in following precautions and to administer proper first aid treatment in case of an
accident.
Ingestion Problem
Consuming small amounts of propylene glycol poses no substantial risks, but intake of greater than 3-4
oz. (or approximately 100 ml.) may cause stomach pain, nausea, or even vomiting. Medical assessment
may reveal hemoglobinuric nephrosis and surface changes in EEG, especially with patients suffering
from kidney problems. Long-term ingestion can cause lactic acidosis and seizures. Give two to four
glasses of water or milk to dilute the substance if ingested. However, DO NOT induce vomiting if taken
in large amounts. Call instead the local poison control center to mitigate the problem and to get proper
guidance. Victim should be constantly monitored for signs of central nervous system dysfunction and
acidosis.
Inhalation Problem
Propylene glycol does not usually cause inhalation problems but can cause breathing difficulties if
used in areas with poor ventilation. Transfer victim immediately in areas with fresh, circulating air.
Supplement with oxygen if symptoms persist and seek medical help.
Skin Exposure
Skin exposure might cause mild irritation. Remove any tainted clothing and wash exposed skin areas
with plenty of water and soap. Irritation subsides usually. Apply an antibacterial cream if exposed areas
develop rashes.
Eye Exposure
Liquid and vaporized propylene glycol can cause mild eye irritation for some people. If it causes stinging
and redness, wash eyes with cold, running water to soothe. Victims should remove and clean contact
lenses and eyeglasses as well.
Chronic exposure
Propylene glycol may be detrimental for the reproductive system and natal development. Laboratory
studies reveal it to be a suspected teratogen. It can also depress the central nervous system if taken in
large doses.
For more detailed information, visit J.T. Baker (http://www.jtbaker.com/msds/englishhtml/p6928.htm)
or the University of Akron database (http://www.jtbaker.com/msds/englishhtml/p6928.htm).
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